Traffic is at a standstill on the Yeager Bridge in Kanawha City, said a Metro 911 dispatcher.
A tractor-trailer ran into the wall of the bridge and "lost its trailer," she said.
The southbound lanes of Interstate 77 are blocked. The trailer is in the fast lane and the cab is still up against the wall.
No injuries have been reported, according to the dispatcher.
The accident was reported at 9:59 a.m.
The Kanawha County Sheriff's Department is responding.